Department of Bioengineering
k.parker@imperial.ac.uk
(44) 0207 594 5171
Department of Bioengineering
Imperial College
London SW7 2AZ, UK
Research links:
• Introduction to wave intensity
• Reservoir/excess pressure
Kim H. Parker
Kim H. Parker is Professor of Physiological Fluid Mechanics (Emeritus). He trained at Princeton University as an aeronautical engineer specialising in combustion and rocketry and was an Assistant Professor in the Mechanics Department at The Johns Hopkins University. He has been studying various aspects of haemodynamics and physiological mechanics since joining the Physiological Flow Studies Unit at IC in 1971. His work in haemodynamics has included the analysis of the wave nature of flow in the arteries, the haemodynamics of the heart and the coupling of flow from the heart to the arteries. His work in connective tissue mechanics has included study of the deformation of the red-blood cell membrane, the osmotic pressure in cartilage and the physicochemical properties of elastin.
Selected Papers
• An introduction to wave intensity analysis (2009)
KH Parker
Med. Biol. Eng. Comput. 47: 175-188
As the title says, this is an introduction to wave intensity analysis. I, the department and the college are grateful for any citations to this paper. See Introduction to Wave Analysis for a web-based introduction.
• Identification of the link between cardiac excess work and cardiovascular events by isolation of arterial reservoir pressure (2010)
JE Davies, KH Parker, G-B Stan, A Malaweera, DP Francis, D Hackett, T Tillin, J Mayet, H Thurston, K Cruickshank, D Collier, A Stanton, P Lacy, B Williams, SM Thom, AD Hughes.
Nature Med. ??: ??-??
The application of wave intensity analysis to clinical data. The integral of the excess pressure over the cardiac period is an independent predictor of cardiac outcomes (heart attack and stroke).
• Red blood cell thermal fluctuations: comparison between experiment and molecular dynamics simulations (2009)
JP Hale, G Marcelli, KH Parker, CP Winlove, PG Petrov
Soft Mattter 5: 3603-3606
The mechanics of the red blood cell membrane are studied using methods developed in molecular dynamics. The magnitude and frequency of the thermal fluctuations of the cell membrane depend on the shear modulus (resistance to in-plane changes of shape) and the bending modulus (resistance to out-of-plane bending.
• Practical methods for noise removal: applications to spikes, nonstationary quasi-periodic noise, and baseline drift. (2009)
D Feuerstein, KH Parker, MG Boutelle
Anal. Chem. 81: 4987-4994
Signal processing methods are developed to analyse noisy signals with peaks. The original application was the analysis of micro-dialysis measurements of brain interstitial glucose and lactate concentration, but is applicable to any signals such as neural spike trains.
Curriculum Vitae
Curriculum vitae
Degrees:
BSE, Aeronautical Engineering, Princeton University, 1962.
MA, Aerospace and Mechanical Engineering, Princeton University, 1964.
PhD, Aerospace and Mechanical Engineering, Princeton University, 1966.
Current Post:
Professor of Physiological Fluid Mechanics (Emeritus)
Department of Bioengineering
Imperial College of Science, Technology and Medicine
Previous Posts:
Reader, PFSG, DBMS, Imperial college, 1989-2001
Lecturer, PFSG, CBMS, Imperial College, 1988-1989.
Honorary Lecturer, PFSU, Imperial College, 1970-1988.
Assistant Professor, Department of Mechanics, The Johns Hopkins University, 1967-1970.
Postdoctoral Fellow, Department of Mechanical Engineering, Imperial College, 1966-1967.
Benefits
Requirements